Therapeutic Antibodies

What are the advantages and disadvantages?

Therapeutic antibody is considered to have the following advantages and disadvantages compared to conventional drugs (low-molecular-weight drugs).


1) Higher specificity to target
=> Higher efficacy and less side effects can be expected.

2) Prolonged half life
=> Infrequent dosage


1) This may increase the economic burden placed on patients
2) Limited route for administration

The above disadvantages may be resolved in the future.

Solution to disadvantage 1)
=>For example, improvements in manufacturing technology may lead to the alleviation of the economic burden of patients.

Solution to disadvantage 2)
=>For example, antibodies with low molecular weight (Fab antibodies, single-chain antibodies, etc.) may be administered in different ways.