ESG Data

Environment
Social
Governance

Environment

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Aspect	Classification	Scope		Unit	FY2016 ^*1	FY2017 ^*1	FY2018 ^*1
CO₂	Emissions (SCOPE1+2)	Plants and Research Laboratories^*2	In Japan	t-CO₂	249,225	249,497	234,540
			Outside Japan	t-CO₂	114,650	115,773	123,676
			Global	t-CO₂	363,875	365,270	358,216
	Emissions year-on-year (SCOPE1+2)		In Japan	%	-1.2	0.1	-6.0
			Outside Japan	%	4.8	1.0	6.8
			Global	%	0.6	0.4	-1.9
	Unit CO₂ emissions		Global	t-CO₂ /billion yen- Sales revenue^*3	105	103	103
	Emissions (SCOPE1)		In Japan	t-CO₂	35,513	37,913	37,648
			Outside Japan	t-CO₂	29,140	30,798	30,378
			Global	t-CO₂	64,652	68,711	68,027
	Emissions (SCOPE2)		In Japan	t-CO₂	213,712	211,584	196,892
			Outside Japan	t-CO₂	85,511	84,975	93,297
			Global	t-CO₂	299,223	296,559	290,189
	Emissions^3 (SCOPE3) Category2,3,8, 10,11,13,14 and 15 are not applicable.	Category1: Purchased goods and services	In Japan	t-CO₂	133,859	133,558	Under calculation
			Outside Japan^*4	t-CO₂	-	33,678	Under calculation
			Global	t-CO₂	-	167,236	Under calculation
		Category4: Transportation and delivery (upstream)	In Japan	t-CO₂	16,998	17,189	Under calculation
			Outside Japan^*4	t-CO₂	-	5,077	Under calculation
			Global	t-CO₂	-	22,266	Under calculation
		Category5: Waste generated erati in opons	In Japan	t-CO₂	11,466	15,773	Under calculation
			Outside Japan^*4	t-CO₂	-	5,140	Under calculation
			Global	t-CO₂	-	20,913	Under calculation
		Category9: Transportation and delivery (downstream)	In Japan	t-CO₂	4,897	1,939	Under calculation
	Emissions (on each site) *Data of major sites in Japan are listed below as "Site data".	Kyowa Hakko Bio Healthcare Product Development Center (Tsukuba)	In Japan	t-CO₂	505	476	456
		Kyowa Hakko Bio Healthcare Plant (Tsuchiura)	In Japan	t-CO₂	328	329	341
		Kyowa Hakko Kirin China Pharmaceutical Co., Ltd.	Outside Japan	t-CO₂	3,027	2,131	1,912
		BioKyowa Inc. (U.S.A.)	Outside Japan	t-CO₂	71,452	75,147	73,480
		Shanghai Kyowa Amino Acid Co., Ltd.	Outside Japan	t-CO₂	21,041	20,779	23,745
		Thai Kyowa Biotechnologies Co., Ltd.	Outside Japan	t-CO₂	19,130	17,716	24,538
Energy	Energy consumption	Plants and Research Laboratories	In Japan	GJ	4,150,606	4,155,927	3,933,206
			Outside Japan	GJ	1,874,131	1,930,679	2,081,019
			Global	GJ	6,024,737	6,086,607	6,014,225
	Energy consumption year-on-year		In Japan	%	-0.8	0.1	-5.4
			Outside Japan	%	9.6	3.0	7.8
			Global	%	2.2	1.0	-1.2
	Unit energy consumption		Global	GJ/billion yen- Sales revenue^*3	1,731	1,722	1,736
	Electricity		In Japan	MWh	177,683	179,488	170,159
			Outside Japan	MWh	110,401	113,427	122,152
			Global	MWh	288,083	292,916	292,311
	City gas		In Japan	1,000m³	8,926	8,747	7,949
			Outside Japan	1,000m³	14,582	15,412	15,175
			Global	1,000m³	23,508	24,160	23,124
	LPG		In Japan	t	391	386	0
			Outside Japan	t	0	0	0
			Global	t	391	386	0
	Heavy oil		In Japan	KL	5,054	4,979	6,030
			Outside Japan	KL	0	0	0
			Global	KL	5,054	4,979	6,030
	Kerosene		In Japan	KL	132	1,423	1,355
			Outside Japan	KL	0	0	0
			Global	KL	132	1,423	1,355
	Diesel oil		In Japan	KL	0.93	0.033	0.019
			Outside Japan	KL	0	0	20.7
			Global	KL	0.93	0.033	20.7
	Steam		In Japan	GJ	1,770,682	1,723,070	1,609,546
			Outside Japan	GJ	208,358	202,242	276,232
			Global	GJ	1,979,040	1,925,312	1,885,777
Renewable energy	Photovoltaic power generation	Plants and Research Laboratories	In Japan	MWh	141	140	169
Water resources	Water used (Total amount)	Plants and Research Laboratories	In Japan	1,000m³	42,979	42,931	38,641
			Outside Japan	1,000m³	9,789	9,545	9,862
			Global	1,000m³	52,768	52,476	48,503
			In Japan	1,000m³	531	547	623
	Water used (Tap water)		In Japan	1,000m³	531	547	623
			Outside Japan	1,000m³	1,317	1,226	1,618
			Global	1,000m³	1,848	1,773	2,241
	Water used (Industrial water)		In Japan	1,000m³	30,506	31,772	29,237
			Outside Japan	1,000m³	70^*5	57^*5	92
			Global	1,000m³	30,576^*5	31,829^*5	29,330
	Water used (Ground water or others)		In Japan	1,000m³	11,941	10,612	8,781
			Outside Japan	1,000m³	8,472	8,319	8,152
			Global	1,000m³	20,413	18,931	16,933
	Unit water used		Global	1,000m³ /billion yen- Sales revenue^*3	15.2	14.8	14.0
	Amount of circulated water usage		In Japan	1,000m³	48,349	52,372	68,416
			Outside Japan	1,000m³	45,842^*5	46,505^*5	51,565
			Global	1,000m³	94,149^*5	98,876^*5	119,981
	Ratio of circulated water usage		In Japan	%			177
			Outside Japan	%	468^*5	487^*5	523
			Global	%	179^*5	188^*5	247
	Wastewater		In Japan	1,000m³	41,779	41,802	40,496
			Outside Japan	1,000m³	9,534	9,304	9,193
			Global	1,000m³	51,312	51,106	49,689
Water pollution	COD	Plants and Research Laboratories	In Japan	t	229	228	239
			Outside Japan	t	838	1007	697
			Global	t	1,066	1,234	936
	Total nitrogen		In Japan	t	250	298	247
			Outside Japan	t	722	683	608
			Global	t	972	981	855
	Total phosphorus		In Japan	t	14	16	12
			Outside Japan	t	-	-	-
			Global	t	14	16	12
Material	Raw material consumption	Plants and Research Laboratories	In Japan	t	105,393	129,910	117,122
			Outside Japan	t	71,905	77,101	68,845
			Global	t	177,298	207,011	185,967
Waste	Waste generated	Plants and Research Laboratories	In Japan	t	36,683	47,326	34,613
			Outside Japan	t	26,353	25,620	26,565
			Global	t	63,036	72,945	61,178
	External recycled waste		In Japan	t	18,952	21,936	22,248
			Outside Japan	t	11,551	13,703	25,264
			Global	t	30,502	36,938	47,512
	Final disposal		In Japan	t	35.3	8.6	1.9
			Outside Japan	t	459.0	225.3	184.0
			Global	t	494.3	233.9	185.9
	Final disposal rate		In Japan	%	0.096	0.018	0.005
			Outside Japan	%	1.7	1.0	0.7
			Global	%	0.8	0.5	0.3
	Basel Convention hazardous wastes		Global		None	None	None
Air	SOx	Plants and Research Laboratories	In Japan	t	6.2	5.9	7.1
			Outside Japan	t	1.5	2.0	2.0
			Global	t	7.8	8.0	9.1
	NOx		In Japan	t	16.1	17.1	17.4
			Outside Japan	t	10.3	11.9	12.8
			Global	t	26.4	28.9	30.2
	Dust		In Japan	t	0.7	0.7	0.8
			Outside Japan	t	4.1	4.9	5.3
			Global	t	4.8	5.5	6.1
	VOC		In Japan	t	488	596	481
	ODS		In Japan	t	0.15	0.15	0.19
PRTR	Releases into the air	Plants and Research Laboratories	In Japan	t	54.6	61.6	56.9
	Releases into the water		In Japan	t	4.5	5.0	5.0
	Releases into the soil		In Japan	t	0	0	0
Management	ISO14001- certified sites	Plants and Research Laboratories	In Japan	Sites	13	13	12
			Outside Japan	Sites	1	1	1
			Global	Sites	14	14	13
	Expensive fines by law violation		Global		None	None	None
External survey	Environmental Management Survey (Nikkei.inc)	Pharmaceutical industry sector	In Japan	Ranking	4	3	3
Site data	Unit energy consumption	Kyowa Kirin Tokyo Research Park	In Japan	KL/m² -Floor area	0.0918	0.0762	0.0700
	CO₂ Emissions			t	4,155	3,354	3,023
	Water used			1,000m³	24	21	19
	Wastewater			1,000m³	21	18	17
	COD			t	-	-	-
	Total nitrogen			t	0.08	0.07	0.06
	Total phosphorus			t	0.00	0.01	0.00
	Waste generated			t	90.7	72.4	79.0
	Final disposal			t	0.0	0.0	0.0
	SOx			t	0	0	0
	NOx			t	0.21	0.21	0.20
	Dust			t	0	0	0
	Unit energy consumption	Kyowa Kirin Fuji Research Park and CMC R&D Center	In Japan	KL/m² -Floor area	0.193	0.184	0.129
	CO₂ Emissions			t	24,731	22,964	16,489
	Water used			1,000m³	2,682	2,636	1,890
	Wastewater			1,000m³	2,198	2,272	1,507
	COD			t	0.82	1.22	1.46
	Total nitrogen			t	2.31	1.93	1.36
	Total phosphorus			t	0.16	0.17	0.08
	Waste generated			t	401	437	237
	Final disposal			t	0.3	0	0.0
	SOx			t	0	0	0
	NOx			t	3.41	3.15	2.80
	Dust			t	0	0	0
	Unit energy consumption	Kyowa Kirin Takasaki Plant	In Japan	KL/m² -Floor area	0.215	0.209	0.215
	CO₂ Emissions			t	23,383	22,327	22,659
	Water used			1,000m³	300	295	315
	Wastewater			1,000m³	300	295	315
	COD			t	0.55	0.51	0.62
	Total nitrogen			t	2.59	2.27	2.62
	Total phosphorus			t	0.24	0.18	0.26
	Waste generated			t	438	371	806
	Final disposal			t	3.0	0.8	0.8
	SOx			t	0	0	0
	NOx			t	2.36	2.00	2.69
	Dust			t	0.05	0.03	0.05
	Unit energy consumption	Kyowa Kirin Ube Plant	In Japan	KL/t- Production output	38.3	26.4	25.7
	CO₂ Emissions			t	7,421	9,349	9,239
	Water used			1,000m³	91	77	78
	Wastewater			1,000m³	-	-	4.26^*6
	COD			t	-	-	0.23^*6
	Total nitrogen			t	-	-	0.00^*6
	Total phosphorus			t	-	-	0.00^*6
	Waste generated			t	137	221	287
	Final disposal			t	0.4	0.6	0.7
	Sox			t	0	0	0
	Nox			t	0	1.68	1.70
	Dust			t	0	0	0
	Unit energy consumption	Kyowa Hakko Bio Yamaguchi Production Center (Hofe)	In Japan	KL/t- Production output	0.84	0.91	0.82
	CO₂ Emissions			t	122,986	123,925	127,302
	Water used			1,000m³	19,434	19,982	19,032
	Wastewater			1,000m³	18,992	19,100	21,096
	COD			t	145	141	167
	Total nitrogen			t	196	241	223
	Total phosphorus			t	5.20	5.10	4.50
	Waste generated			t	14,011	16,013	16,164
	Final disposal			t	31.2	0.0	0.0
	SOx			t	0	0	0.00
	NOx			t	0.90	0.99	1.65
	Dust			t	0.01	0.02	0.02
	Unit energy consumption	Kyowa Hakko Bio Yamaguchi Production Center (Ube)	In Japan	KL/t- Production output	5.61	5.60	5.50
	CO₂Emissions			t	35,087	35,631	25,816
	Water used			1,000m³	16,522	16,518	14,500
	Wastewater			1,000m³	16,281	16,624	14,626
COD	t			71	80	66
Total nitrogen	t			27.9	28.6	13.7
Total phosphorus	t			5.19	6.33	4.24
Waste generated	t			20,005	28,561	14,200
Final disposal	t			0.3	0.2	0.3
SOx	t			0.78	0.17	0.57
NOx	t			0.72	0.21	0.58
Dust	t			0.07	0.02	0.06
Unit energy consumption	Kyowa Pharma Chemical	In Japan	KL/t- Production output	11.5	10.4	14.0
CO₂ Emissions			t	26,791	27,498	29,216
Water used			1,000m³	3,855	3,336	2,801
Wastewater			1,000m³	3,957	3,462	2,926
COD			t	11.30	4.70	3.9
Total nitrogen			t	21.3	24.3	6.3
Total phosphorus			t	3.03	4.05	3.30
Waste generated			t	1,505	1,579	2,810
Final disposal			t	0.0	0.1	0.0
SOx			t	5.45	5.71	6.57
NOx			t	6.51	6.82	7.76
Dust			t	0.53	0.55	0.63

*1:
Data is from January to December. Amounts are rounded. As a result, the sum and breakdown of data may not equal the totals.
*2:
In Japan, the plants and research laboratories of Kyowa Kirin, Kyowa Medex (excluded in 2018 due to deconsolidation), Kyowa Hakko Bio and Kyowa Pharma Chemical are covered. Overseas, the plants of Kyowa Hakko Kirin China Pharmaceutical, BioKyowa (U.S.A.), Shanghai Kyowa Amino Acid, and Thai Kyowa Biotechnologies are covered.
*3:
Sales revenue data have been calculated based on the International Financial Reporting Standards (IFRS).
*4:
We have disclosed overseas data since 2017.
*5:
Data has been revised as a change of scope and a result of data review.
*6:
Kyowa Kirin Ube Plant started drainage to the public sewer from 2018. Until 2017, it was drained to Kyowa Hakko Bio Yamaguchi Production Center (Ube) located on the same site.

Social

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Aspect	Classification	Items	Scope	Unit	FY2016	FY2017	FY2018
Compliance	Number of reports to hotline		In Japan	Cases	30	29	20
Research and development	R&D expenses	R&D expenses	Consoli dated	¥ billion	538	492	486
Research and development	R&D expenses	Rate of R&D expenses to net sales	Consoli dated	%	15.7	13.9	14.0
Business Partners	Questionnaires about CSR	Number of responded companies	In Japan	Compa nies	259	343	440
Employees	Number of employees by region	In Japan	In Japan	Persons	5,766	5,729	5,269
		Outside Japan	In America	Persons	378	391	424
			In Europe	Persons	546	612	678
			In Asia	Persons	775	800	871
		Total	Consoli dated	Persons	7,465	7,532	7,242
	Employee data	Number of men employees	Non- consoli dated	Persons	2,917	2,848	2,768
		Number of women employees	Non- consoli dated	Persons	1,171	1,177	1,150
		Total	Non- consoli dated	Persons	4,088	4,025	3,918
		Average years of service (men)	Non- consoli dated	Years	17.9	18.4	18.8
		Average years of service (women)	Non- consoli dated	Years	16.8	17.4	17.4
		Total	Non- consoli dated	Years	17.6	18.1	18.4
		Average age	Non- consoli dated	Age	42	42.5	42.8
		Average annual salary	Non- consoli dated	Yen	8,329,277	8,369,461	8,562,688
		The number of new hires	Non- consoli dated	Persons	71	99	90
		Average number of actual hours worked	Non- consoli dated	Hours	1,847	1,840	1,840
		Full-time staff turnover rate ^*1	Non- consoli dated	%	5.55	4.2	4.5
	Diversity	Number of disabled employees^*2	In Japan	Persons	148	150	143
		Ratio of disabled employees^*2	In Japan	%	2.29	2.33	2.45
		Number of women managers	Non- consoli dated	Persons	85	91	101
		Ratio of women managers^*3	Non- consoli dated	%	7.1	7.8	8.9
	Special holiday / leave	Men taking child care leave	Non- consoli dated	Persons	3	6	3
		Women taking child care leave	Non- consoli dated	Persons	110	101	100
		Total	Non- consoli dated	Persons	113	107	103
		Reduced work hour for childcare (men)	Non- consoli dated	Persons	0	0	0
		Reduced work hour for childcare (women)	Non- consoli dated	Persons	94	99	79
		Total	Non- consoli dated	Persons	94	99	79
		Numbers taking nursing care leave	Non- consoli dated	Persons	84	93	56
	Occupational health and safety management^*4	Total annual hours worked	In Japan	Hours	5,293,514	5,203,240	5,579,750
		Accident frequency rate	In Japan	-	0.19	0.19	0.36
		Accident severity rate	In Japan	-	0.009	0.005	0.011
		Number of fatalities	Employees	Persons	0	0	0
		Number of fatalities	Contractors	Persons	0	0	0
		Number of participants in safety manager training ^*5	In Japan	Persons	34	37	36
	Rate of participation in a labor union		In Japan	%	100	100	100
Shareholders	Dividends per share	Interim	Non- consoli dated	Yen	12.50	12.50	15.00
		Year–end	Non- consoli dated	Yen	12.50	14.50	20.00
		Total	Non- consoli dated	Yen	25.00	27.00	35.00
Community	Number of participants in Bio Adventure activities		Non-consoli dated	Persons	459	446	549

*1:
The number of employees who left the organization during this reporting period / the total number of full-time employees at the end of the reporting period (including employees who leave the organization voluntarily or due to dismissal, retirement, or death in service).
*2:
As of June each year. The figures are for the Kyowa Kirin Group (domestic).
*3:
The data is calculated based on the new criteria from 2015.
*4:
The plants and research laboratories of Kyowa Kirin, Kyowa Medex, Kyowa Hakko Bio and Kyowa Pharma Chemical are covered.
*5:
data is for April to March of the following year.

Governance

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Aspect	Classification	Items	Scope	Unit	FY2016	FY2017	FY2018
Governance	Structure of board of directors	Number of directors	Non- consoli dated	Persons	8	8	7
		Number of outside directors	Non- consoli dated	Persons	2	2	2
		Number of woman directors	Non- consoli dated	Persons	1	1	1
	Structure of board of company auditors	Number of company auditors	Non- consoli dated	Persons	5	5	5
	Structure of board of company auditors	Number of outside company auditors	Non- consoli dated	Persons	3	3	3
	Compensation of directors	Total^*1	Non- consoli dated	¥ Million	323	391	373
	Compensation of statutory auditors	Total^*2	Non- consoli dated	¥ Million	25	26	26

*1:
Compensation of the members, excluding outsaide directors are covered.
*2:
Compensation of the members, excluding outside company auditors are covered.