Efforts to Create a Sustainable Society

The Kyowa Kirin Group actively engages in efforts to protect the global environment as a prerequisite for business continuity, and advances activities to realize a sustainable society. Among the materiality issues, we have identified "Responding to Climate Change" as an important environmental initiatives to be undertaken by the Kyowa Kirin Group, and we are continuously implementing various measures to reduce greenhouse gas emissions across our entire value chain.

The Kyowa Kirin Group recognizes that the effects of climate change pose risks and opportunities for business continuity, and we have positioned this as one of our key management issues. In light of global social demands, including the transformation to a decarbonized society under the Paris Agreement, our group will work to reduce CO₂ emissions. The Kyowa Kirin Group's policy on climate change is clearly stated in the “Kyowa Kirin Group Environmental Policy” as “an important environmental initiatives to be undertaken by the Kyowa Kirin Group.”
In 2020, Kirin Group formulated the Kirin Group Environmental Vision 2050 as a new long-term strategy for strengthening social and corporate resilience. In pursuit of “a society that has overcome climate change” that constitutes the society of 2050 that we want to create together with respect to climate change described in the Kirin Group Environmental Vision 2050, Kirin Group has set a target of reducing greenhouse gas (GHG) emissions for the entire value chain to net zero and is working with stakeholders to reduce GHG emissions and take the lead in building a decarbonized society. Kirin Group as a whole has set the more specific medium- to long-term goals of reducing its GHG emissions to 50% (Scope 1 and 2) and to 30% (Scope 3) of their 2019 levels by 2030, joining RE100, and achieving a 100% reliance on renewable energy for electric power by 2040, and it is developing various measures designed to accomplish these.
Kyowa Kirin Group, like the Kirin Group, has also set the goal of achieving net zero GHG emissions for the entire value chain by 2050 in order to realize a "society that overcomes climate change". As more specific medium- to long-term targets, we have set the goals of achieving 100% use of renewable energy for electricity by 2040 and reducing CO₂ emissions by 55% (Scope 1 and 2) and by 30% (Scope 3) by 2030 compared with 2019. Kyowa Kirin Group will help realize this “society that has overcome climate change” by utilizing the Kirin Group’s global network to actively put in place climate change measures that take advantage of the characteristics of its business.

Furthermore, Kyowa Kirin Group has a new vision for 2030. To fulfill this new vision, we have established “retaining the trust of society” as one of the strategies in our Medium-term Business Plan, with “helping to protect the global environment” being one of the measures to be pursued to that end. Our specific commitments pertaining to climate change include working to reduce CO₂ emissions as soon as possible with a particular focus on energy-saving approaches inclusive of capital investment as well as expanded use of renewable energies, and to make an energy transition.

In collaboration with Kirin Holdings Co., Ltd, the Kyowa Kirin Group has set a new target for 2030 CO₂ emissions (Scope 1 + 2) for the Kyowa Kirin Group alone, "55% reduction from 2019 levels," as a new indicator based on the Science Based Targets (SBT) 1.5°C target. In addition, we have established a roadmap for achieving this target, and also set a short-term target (CO₂ emissions in FY2025: 63% reduction from 2019 levels). Meanwhile, for Scope 3, we have set a target for CO₂ emissions in 2030 (Scope 3) of "30% reduction from 2019 levels" and have also established a roadmap.

We will undertake continuous energy-saving activities, including capital investment, through 2030 while taking advantage of the fact that most of the energy our business uses is electricity to accelerate the introduction and expansion of renewable energy and achieve effective CO₂ emission reductions, and we will review the roadmap every year to verify the effectiveness of our measures in achieving our target. Specifically, our Group will implement the following measures.

In 2024, we endeavored to reduce CO₂ emissions to achieve our 2030 target (Scope 1 + 2)^*1 and to reduce our energy intensity by 1% or more from the previous year.
In 2024, we have introduced renewable energy that meets the RE100 standard at the Tokyo Research Park, and we have also introduced solar power generation equipment at the new building at the Takasaki Plant, and we are continuing to promote the reduction of CO₂ emissions.
For details, please refer to "Major Initiatives: Promoting the Introduction of Renewable Energy" below.
Furthermore, we have set annual energy intensity reduction targets for each site, and have deployed measures to increase production efficiency. Energy intensity in FY2024 was 5.4% lower than in the previous year (global target: 1% reduction year-on-year), a significant improvement over the target.
As a specified business operator under the Act on the Rational Use of Energy, we are obligated to make efforts to reduce energy intensity by an average of 1% per year, and we have maintained an S-class rating (target achievement) for 6 consecutive years under the Act on the Rational Use of Energy’s business operator classification system (SABC Evaluation System).
Various data on CO₂ emissions are available in the ESG Data Collection.

ESG Data Collection

While continuing the above-mentioned measures through 2030, we will be pursuing an energy transition away from fossil fuels with the aim of net zero CO₂ emissions for the entire value chain.

In an effort to promote the wider use of renewable energy, Kyowa Kirin has been installing solar power generation facilities since 2011. As of 2024, the Takasaki Plant, Tokyo Research Park, Fuji Site and etc. have solar power generation systems in operation, generating a total of 461,000 kWh of solar power and reducing CO₂ emissions by 262 tons^*1.
In March 2023, we have introduced and began operating a large-scale solar power generation facility (1.47 MW) based on the on-site PPA model at the Ube Plant, contributing to a significant reduction in CO₂ emissions.
On the other hand, from 2020 onwards, we have been gradually introducing RE100-compliant renewable energy at the Takasaki Plant, Tokyo Research Park, Fuji Site, and Ube Plant, and have completed the switch to 100% renewable energy for all major domestic sites^*2,3,4. As a result of introducing these renewable energies, in FY2024, approximately 73,900,000 kWh of the Kyowa Kirin Group's annual electricity consumption of approximately 77,400,000 kWh was switched to renewable energy sources with zero CO₂ emissions, and when combined with the reduction effect of various energy-saving measures, approximately 65% (approximately 33,700 tons) of the Group's annual CO₂ emissions were reduced^*5.
In addition, the RE100-compliant renewable energy has been also introduced at the head office and Kyowa Kirin USA Holdings, Inc./ Kyowa Kirin, Inc. in 2021^*6.

We plan to push forcefully ahead in introducing and expanding renewable energy use to achieve our 2030 target.
Going forward, the plan is for us to have switched to 100% renewable energy at all of our group sites, including overseas sites and domestic branch offices, by 2030. In addition, we will continue to expand the installation of solar power generation facilities at production and research sites in Japan and overseas.

Kyowa Kirin Group has been replacing its commercial vehicles from conventional low-emission certified vehicles to hybrid vehicles in phases since 2009. Starting in 2019 onward, all newly introduced domestic sales vehicles (company vehicles) are equipped with hybrid cars, resulting in the completion of the introduction of hybrid cars in all domestic sales vehicles (achieving a 100% hybrid car adoption rate) as of the end of FY2023. We have thus reduced the amount of fuel used for sales activities and cut our CO₂ emissions. At the same time, we have continued to make significant reductions in CO₂ emissions by implementing new information provision activities such as web-based interviews, information sessions and lectures. We will consider the relationship between information provision activities and the environmental impact and proceed with efforts toward the realization of a low-carbon corporate group.

ESG Data

We continue to work on reducing Scope 3 emissions to achieve our goal of “net zero greenhouse gas emissions across the value chain by 2050”. In 2024, we set a new target to reduce Scope 3 emissions by 30% in 2030 compared to 2019, and we have created a roadmap to achieve this goal. We calculate Scope 3 emissions by dividing them into 15 categories in accordance with the Ministry of the Environment‘s guidelines, which are consistent with the GHG Protocol. We will first focus on reducing emissions from outsourced manufacturing (Category 1), which is a particularly large source of Scope 3 emissions, and will work on this in cooperation with our suppliers. We have also started to interview our suppliers about their activities and responses to climate change.

We support laws, regulations and policies pertaining to climate change and reduced energy consumption at all our business locations inside and outside Japan (e.g., the Act on Promotion of Global Warming Countermeasures (“Global Warming Act”) and the Act on the Rationalization etc. of Energy Use (“Energy Saving Act”) in Japan) and take appropriate measures to comply with them.
In addition, we are a Specified Business Operator under the Energy Saving Act, and we are thus obliged to try for an average reduction in unit energy consumption of 1% per year. Every year, we have achieved reductions in unit energy consumption by setting unit energy consumption reduction targets for individual sites and implementing various energy-saving measures. We have maintained an S-class evaluation (target achieved) under the Energy Saving Act’s business operator classification system (SABC evaluation system) for 6 years running.

We are a member of the Federation of Pharmaceutical Manufacturers' Associations of Japan (FPMAJ) and its affiliate the Japan Pharmaceutical Manufacturers Association (JPMA). Both the FPMAJ and the JPMA are taking part in the "Carbon Neutrality Action Plan” (formerly “Commitment to a Low Carbon Society”) developed by the Japan Business Federation. We support the Carbon Neutrality Action Plan and we have been participating in Carbon Neutrality Action Plan (Phase II)^*1 with a target year of 2030.
We serve as a member on the newly established Environmental Issue Committee of the Japan Pharmaceutical Manufacturers Association (JPMA). Through these activities, we are indirectly lobbying the government by reflecting our views in industry groups' policy recommendations on climate change issues, such as formulating CO₂ emission reduction targets.
On the other hand, in order to achieve excellence in safety, environmental and social performance across the entire supply chain of pharmaceutical and healthcare companies, it is necessary to build a robust supply chain that meets the demands of society, and from the perspective of sustainable procurement, we joined the Pharmaceutical Supply Chain Initiative (PSCI)^*2 in July 2024 to promote these initiatives and address issues across the industry as a whole.
To ensure consistency with the stances of industry groups on climate change strategies, we are participating and gathering information in seminars on climate change hosted by the Ministry of Economy, Trade and Industry, the Ministry of the Environment, the Ministry of Health, Labour and Welfare and other government organizations as well as in seminars sponsored by industry groups. We are also taking part as members in a variety of relevant groups to discuss climate change issues and share the content of these discussions internally. We check that this content is in line with our own positions and approaches, and any discrepancies are taken up with the in-house organizations responsible for environmental management and then coordinated via the Group CSR Committee chaired by the Representative Director and Executive Vice President. Through this process, we are aligning our climate change strategies with industry group activities.

Kirin Holdings Co., Ltd. joined RE100^* in 2020 and thereby committed to switching to 100% renewable energy use by 2040. Our Group's climate change measures are consistent with those of Kirin Holdings, and our Group will also be working to introduce renewable energy in order to fulfill this commitment. In July 2022, Kirin Holdings became the first food company in the world to be certified as "SBT Net Zero" by the SBT Initiative. The certification was granted on the grounds that the long-term goal of "reducing GHG emissions throughout the value chain to net zero by 2050" set forth in the Kirin Group Environmental Vision 2050 is a scientifically-based goal that is consistent with the level of GHG emission reductions required by the Paris Agreement. Kirin Holdings has obtained certification of its SBT 1.5°C target as well, and our Group’s 2030 target has been set to conform to these.

Water is an important resource that is indispensable for manufacturing pharmaceutical products. However, global water cycle abnormalities, intertwined with climate change and other problems, cause regional disasters such as droughts and floods.

In keeping with the Kyowa Kirin Group Environmental Policy, Kyowa Kirin Group is endeavoring to save water and conserve water sources in pursuit of a “society that values sustainable water resources", depicted as the society we want to create by 2050 in the Kirin Group Environmental Vision 2050.

Kyowa Kirin Group assesses the water risks (water shortage, water stress, flooding, water source contamination risk assessments) faced by its production sites on a five-point scale^*?based on their water consumption data, water risk assessment tools (WRI Aqueduct and WWF Water Risk Filter), and Internet/questionnaire surveys.
It was found as a result that the Ube Plant (Yamaguchi Prefecture) was at higher risk than other production sites (4 on a 5-point scale). The Ube Plant takes its water from the Koto River, which is frequently subject to droughts, and a hazard map created by the city of Ube where the plant is located predicts flooding of up to five meters due to storm surges. As for our mainstay Takasaki Plant inundation damage was envisioned using the latest site-specific inundation simulation conducted by the Ministry of Land, Infrastructure, Transport and Tourism.
Based on these findings, we are working to avoid and minimize these risks by adopting “software” measures such as reviewing and formulating large-scale natural disaster BCPs at sites, as well as “hardware” measures aimed at inundation prevention (e.g., geographically distributing the storage of important production-related assets, waterproofing buildings, installing key equipment on off-ground floors or on high ground, and installing tide embankment) to avert damage to the equipment itself.
The total water intake at the Ube Plant determined by the water risk assessment to be subject to high risk of water shortages and water stress, for FY2024 was 85,000 tons, amounting to about 5.8% of the Kyowa Kirin Group’s total water intake of 1,465,000 tons. However, the intake of high-quality fresh water needed for operation by Ube Plant is currently sustainable, and the business activities of this plant are not adversely affected by water shortages and water stress.
Furthermore, the Ube Plant works to promote groundwater recharge in the water intake area through its annual "Water Source Forest Activity."

Assessment indicator: Very High, High, Medium, Low, Very Low

Ube Plant : Tide Embankment

In order to develop measures tailored to the characteristics of our business and promote specific water conservation activities, we have set a target of reducing water intake by 40% from the 2019 level by 2030 for the Kyowa Kirin Group.
We are also working to improve the efficiency of water use by setting and managing yearly unit water intake targets for individual sites. In 2024, the Kyowa Kirin Group reduced its water intake per unit by 0.4% compared to the previous year.

Kyowa Kirin Group is working to improve the efficiency of water use in its manufacturing processes. We are striving to reduce the amount of water we use by recycling and reusing water. More specifically, we are improving the quality of cooling tower cooling water, changing and optimizing drainage blow settings, and optimizing scrubber makeup water settings.

We generated 803,000 m³ of wastewater in 2024, 700,000 m³ of which was drained into rivers. We have set voluntary management standards for draining water into rivers that are stricter than the drainage standards set by the competent government authorities, and we are constantly monitoring to prevent discharges of harmful substances and high-load wastewater. Specifically, Kyowa Kirin Group is aggressively upgrading its manufacturing processes and making capital investments in wastewater treatment facilities, and we have continued to reduce COD (chemical oxygen demand), nitrogen, and phosphorus, all wastewater pollution indicators. We are working to prevent water pollution by optimizing wastewater treatment for all types of wastewater, monitoring treatment status, and extracting metal-containing wastewater for industrial waste treatment to prevent discharges of high-load and toxic substances in wastewater.
We were not subject to any fines, legal orders, or other penalties for violating water intake/drainage- or other water-related regulations in 2024.

Under the Kyowa Kirin Group Environmental Policy, we are working to strengthen our waste management system and are also promoting various initiatives to reduce the amount of waste generated and to recycle waste, with the goal of creating a resource-recycling society.
Our Group makes it a rule to not only audit waste disposal service providers upon concluding contracts with them, but also to conduct periodic audits to check that their services are of high quality in order to help prevent illegal dumping. In addition, Group-wide efforts are made to enhance awareness of waste governance, such as by providing waste management personnel with ongoing education. In addition, we have also set targets for recycling to ensure the promotion of resource recycling.

To realize a resource-recycling society, the Kyowa Kirin Group has set a recycling rate target for plastic waste of 65% (by 2030)^*1,2 and is considering and developing various measures.

Waste generated across the entire Kyowa Kirin Group’s sites in Japan^*1 reached 981 tons in 2024. The final landfill disposal volume was reduced to 0.03 tons in 2024, accounting for 0.003% of the waste generated. Zero emission^*2 was therefore achieved. We will continue with our efforts to reduce waste.

Regarding the proper disposal of PCBs, we have completed the disposal of high-concentration PCB waste such as condensers, transformers, circuit breakers, and lighting ballasts used in the past in accordance with laws and regulations by the deadline.
Low-concentration PCB waste is stored in accordance with the storage standards for specially controlled industrial waste, locked in a warehouse with underground seepage prevention, and disposed of in accordance with laws and regulations by the deadline.

In striving to reduce emissions of chemical substances, the Kyowa Kirin Group has focused its activities on reducing emissions of volatile organic compounds (VOCs).
As a result, the Kyowa Kirin Group's overall domestic VOC emissions remained at a very low level of 0.02 tons as of 2024. We will continue with our efforts to modify our production processes to eliminate the use of VOCs and, when installing new facilities using VOCs, to concurrently install highly efficient VOC removal facilities.

The total emission of Class I designated chemical substances of the entire Kyowa Kirin Group in Japan in 2024 under the PRTR Act was 0.001 tons (0.02 tons in the previous fiscal year), which remains at a low level. We are also appropriately managing chemical substances other than PRTR Act-designated Class I chemical substances in compliance with relevant laws and regulations. We will continue our efforts to control chemical substance emissions.

Details on emissions of PRTR Act-designated Class I chemical substances are available in the ESG Data Collection.

ESG Data Collection

Kyowa Kirin Group is taking rigorous measures to switch fuel sources for boilers and make capital investments to maintain emissions of sulfur oxides (SOx), nitrogen oxides (NOx) and dust, which are indices of air pollution, at low levels.

Preserving the water resources that sustain the interconnection of lives helps maintain the ecosystem and preserve biodiversity.

As part of its activities to conserve the ecosystem and biodiversity, Kyowa Kirin Group has been endeavoring to preserve water by engaging in the Kirin Group’s water-source preservation project since FY2007. The Takasaki Plant, the mainstay plant for pharmaceuticals, and the Ube Plant perform weeding and tree thinning every year in an effort to preserve forests that provide water resources.

The Takasaki Plant entered into a three-party agreement with Gunma Prefecture and Kurabuchi Furusato Public Corporation, under which it has been engaging in the Kyowa Kirin Takasaki Water Source Forest Conservation Activities. In 2024, the Takasaki Plant received an award from the Minister of the Environment (for its contributions to regional environmental conservation) in recognition of its 17 years of its forest conservation activities, as well as its efforts to create a green factory with excellent landscaping by planting a variety of tree species in harmony with the factory and surrounding roads.

News release: Kyowa Kirin's Takasaki Plant received the 2024 Minister of the Environment Award (Contribution to Regional Environmental Conservation) (in Japanese only)

We also continue to participate in activities in cooperation with local government organizations, such as the Satoyama Biotope Futamatase Conservation Project in Ube City, Yamaguchi Prefecture, the River Friendship System in Shizuoka Prefecture, which involves cleaning up local rivers, and the Mt. Fuji Garbage Reduction Campaign. In addition, each site participates in ecosystem protection activities with local people, such as the release of juvenile Amago trout, the protection and care of Akiyoshidai grasslands, the Sakaigawa River Cleanup Campaign, and park cleanup activities with neighboring companies. Through these activities, we will continue to support local communities and raise awareness about beautifying the natural environment and preserving biodiversity.

We comply with the Kirin Group’s Guidelines on Access to Genetic Resources in gaining access to raw materials and specimens and sharing the benefits arising out of their use with local communities that provide them.
Furthermore, to comply with the Act on the Conservation and Sustainable Use of Biological Diversity through Regulations on the Use of Living Modified Organisms (Cartagena Act), we have put in place an internal committee to conduct proper management.

The Kirin Group Action Plan for the Sustainable Use of Biological Resources declares that the Group will be using paper confirmed to be from sustainable sources for 100% of paper containers and packaging by 2030, with all other paper being recycled paper or paper whose production has been verified as taking sustainability into consideration, and the Kyowa Kirin Group has been introducing FSC^®-certified products^* under this plan.
At Kyowa Kirin, we are using our procurement activities to help protect the world’s forests. Specifically, we have adopted FSC^®-certified products for materials such as company envelopes, company brochures, and cardboard product packaging. In accordance with the Kirin Group Action Plan for Sustainable Use of Biological Resources, which was revised in 2021, we continue to study applications for FSC^®-certified products. In addition to expanding their use for domestic product packaging cardboard boxes, we are considering using them for materials such as product inner boxes. We are also considering the use of FSC^®-certified products overseas, at business sites and for products.

Kyowa Kirin has acquired FSC^® promotion license (FSC^® N003037).